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Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

February 1, 2026February 1, 2026
Weekly Roundup – January 31, 2026

Weekly Roundup – January 31, 2026

January 31, 2026February 1, 2026
Embedding clinical intelligence to help close care gaps

Embedding clinical intelligence to help close care gaps

January 31, 2026January 31, 2026
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

January 31, 2026January 31, 2026
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Tag: Validation

Next-generation AI framework for comprehensive oral leukoplakia evaluation and management

Next-generation AI framework for comprehensive oral leukoplakia evaluation and management

August 10, 2025August 11, 2025npj Digital Medicine

Oral potentially malignant disorder poses a significant risk of malignant transformation, particularly in cases with epithelial dysplasia (OED). Current OED assessment methods are invasive and lack reliable decision-support tools for cancer risk evaluation and…

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Multimodal deep learning model for prognostic prediction in cervical cancer receiving definitive radiotherapy: a multi-center study

Multimodal deep learning model for prognostic prediction in cervical cancer receiving definitive radiotherapy: a multi-center study

August 4, 2025August 4, 2025npj Digital Medicine

For patients with locally advanced cervical cancer (LACC), precise survival prediction models could guide personalized treatment. We developed and validated CerviPro, a deep learning-based multimodal prognostic model, to predict disease-free survival (DFS) in 1018…

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Predicting outcomes following endovascular aortoiliac revascularization using machine learning

Predicting outcomes following endovascular aortoiliac revascularization using machine learning

July 24, 2025July 24, 2025npj Digital Medicine

Endovascular aortoiliac revascularization is a common treatment option for peripheral artery disease that carries non-negligible risks. Outcome prediction tools may support clinical decision-making but remain limited. We developed machine learning algorithms that predict 30-day…

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The Validation Process Bottleneck

The Validation Process Bottleneck

July 23, 2025July 24, 2025Healthcare IT Today

#healthit #healthcare #dimensionalinsight…

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Modeling trajectories of routine blood tests as dynamic biomarkers for outcome in spinal cord injury

Modeling trajectories of routine blood tests as dynamic biomarkers for outcome in spinal cord injury

July 22, 2025July 22, 2025npj Digital Medicine

Routinely collected blood tests can reflect underlying pathophysiological processes. We demonstrate that the dynamics of routinely collected blood tests hold prediction validity in acute Spinal Cord Injury (SCI). Using MIMIC data (n = 2615) for modeling…

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Systematic review and meta-analysis of deep learning for MSI-H in colorectal cancer whole slide images

Systematic review and meta-analysis of deep learning for MSI-H in colorectal cancer whole slide images

July 19, 2025July 19, 2025npj Digital Medicine

This meta-analysis evaluated diagnostic performance of deep learning (DL) algorithms using whole slide images (WSIs) for detecting microsatellite instability-high (MSI-H) in colorectal cancer (CRC). PubMed, Embase, and Web of Science were searched until January…

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Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model

Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model

July 19, 2025July 19, 2025npj Digital Medicine

Artificial intelligence applications in liver pathology remain limited, with existing tools either narrowly focused or lacking external validation. This study introduces HOTSPoT, an open-source, validated transformer-based model for automated segmentation of portal tracts in…

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Predictive modeling for step II therapy response in periodontitis - model development and validation

Predictive modeling for step II therapy response in periodontitis – model development and validation

July 16, 2025July 16, 2025npj Digital Medicine

Steps I and II periodontal therapy is the first-line treatment for periodontal disease, but has varying success. This study aimed to develop machine learning models to predict changes in periodontal probing depth (PPD) after…

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Deep adaptive learning predicts and diagnoses CSVD-related cognitive decline using radiomics from T2-FLAIR: a multi-centre study

Deep adaptive learning predicts and diagnoses CSVD-related cognitive decline using radiomics from T2-FLAIR: a multi-centre study

July 16, 2025July 16, 2025npj Digital Medicine

Early identification of cerebral small vessel disease related cognitive impairment (CSVD-CI) is crucial for timely clinical intervention. We developed a Transformer-based deep learning model using white matter hyperintensity (WMH) radiomics features from T2-fluid-attenuated inversion…

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Phenotypic screening and genetic insights for predicting major vascular-related diseases using retinal imaging

Phenotypic screening and genetic insights for predicting major vascular-related diseases using retinal imaging

July 15, 2025July 15, 2025npj Digital Medicine

Retinal photography is a valuable non-invasive tool for assessing vascular health, but genetic evidence linking retinal microcirculation to major vascular-related diseases (e.g., myocardial infarction [MI], stroke, and chronic kidney disease [CKD]) remains scarce. This…

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