Sepsis is the leading cause of mortality in burn patients, yet early identification remains difficult due to persistent hyperinflammatory responses and altered baseline physiology. We developed a streamlined machine learning model for early sepsis…
Continue Reading
Artificial intelligence (AI) tools for radiology are commonly unmonitored once deployed. The lack of real-time case-by-case assessments of AI prediction confidence requires users to independently distinguish between trustworthy and unreliable AI predictions, which increases…
Continue Reading
Continuous prediction of glucose levels and hypoglycemia events is critical for managing type 1 diabetes mellitus (T1DM) under intensive insulin therapy. Existing models focus on a single task, limiting their practicality and adaptability in…
Continue Reading
Recent advances in artificial intelligence, particularly large language models (LLMs), show promise for mental health applications, including the automated detection of depressive symptoms from natural language. We fine-tuned a German BERT-based LLM to predict…
Continue Reading
Generative artificial intelligence is revolutionizing digital twin development, enabling virtual patient representations that predict health trajectories, with large language models (LLMs) showcasing untapped clinical forecasting potential. We developed the Digital Twin—Generative Pretrained Transformer (DT-GPT),…
Continue Reading
Carotid atherosclerosis is a key predictor of cardiovascular disease (CVD), necessitating early detection. While foundation models (FMs) show promise in medical imaging, their optimal selection and fine-tuning strategies for classifying carotid atherosclerosis from retinal…
Continue Reading
Predicting multiple postoperative complications remains challenging in perioperative care. Current approaches often address complications individually, limiting the potential for integrated risk assessment. We developed and externally validated a scalable, interpretable, tree-based multitask learning model…
Continue Reading
Healthcare and life sciences are entering a new phase of digital transformation, powered by the rise of agentic artificial intelligence. Unlike traditional AI tools that focus on prediction or classification, agentic AI combines decision-making…
Continue Reading
Dynamic response to therapy is strongly associated with cancer outcomes. We aim to develop the response-adapted individualized risk index (RAIRI) as an individual prognostic approach and predictive biomarker for adjuvant chemotherapy (AC) benefit in…
Continue Reading
Timely care in a specialised neuro-intensive therapy unit (ITU) reduces mortality and hospital stays. Planned admissions to ITU following surgery are safer than unplanned ones. However, post-operative care decisions remain subjective. This study used…
Continue Reading
