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Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

February 1, 2026February 1, 2026
Weekly Roundup – January 31, 2026

Weekly Roundup – January 31, 2026

January 31, 2026February 1, 2026
Embedding clinical intelligence to help close care gaps

Embedding clinical intelligence to help close care gaps

January 31, 2026January 31, 2026
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

January 31, 2026January 31, 2026
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Tag: Medicine

Transforming healthcare delivery with conversational AI platforms

Transforming healthcare delivery with conversational AI platforms

September 30, 2025September 30, 2025npj Digital Medicine

Healthcare communication faces unprecedented challenges as the healthcare workforce is increasingly faced with increased administrative burdens and reduced time with patients. Conversational agents powered by generative AI may offer a potential solution by collecting…

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Optimizing large language models for detecting symptoms of depression/anxiety in chronic diseases patient communications

Optimizing large language models for detecting symptoms of depression/anxiety in chronic diseases patient communications

September 30, 2025September 30, 2025npj Digital Medicine

Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…

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Comparison of SHAP and clinician friendly explanations reveals effects on clinical decision behaviour

Comparison of SHAP and clinician friendly explanations reveals effects on clinical decision behaviour

September 26, 2025September 26, 2025npj Digital Medicine

Clinical decision-making substantially impacts patients’ lives and their quality of life. However, the black-box nature of AI-powered clinical decision support systems (CDSSs) complicates the interpretation of how decisions are derived. Explainable AI (XAI) improves…

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TIMER: temporal instruction modeling and evaluation for longitudinal clinical records

TIMER: temporal instruction modeling and evaluation for longitudinal clinical records

September 26, 2025September 26, 2025npj Digital Medicine

Electronic health records (EHRs) contain rich longitudinal information for clinical decision-making, yet LLMs struggle to reason across patient timelines. We introduce TIMER (Temporal Instruction Modeling and Evaluation for Longitudinal Clinical Records), a method to…

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Ophthalmic drug discovery and development using artificial intelligence and digital health technologies

Ophthalmic drug discovery and development using artificial intelligence and digital health technologies

September 25, 2025September 25, 2025npj Digital Medicine

Globally, drug discovery and development programs are complex, multi-decade long and prohibitively expensive. Artificial intelligence (AI) and other digital health technologies have the potential to enhance and accelerate each stage of drug discovery and…

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Soft, all-in-one, nanomembrane wearable system for advancing neonatal health monitoring in Ethiopia

Soft, all-in-one, nanomembrane wearable system for advancing neonatal health monitoring in Ethiopia

September 25, 2025September 25, 2025npj Digital Medicine

The neonatal period is critical and stressful, particularly in low-resource settings where existing monitoring methods for newborns are sporadic and labor-intensive. There is a pressing need for an affordable, user-friendly device that offers continuous…

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Quality safety and disparity of an AI chatbot in managing chronic diseases: simulated patient experiments

Quality safety and disparity of an AI chatbot in managing chronic diseases: simulated patient experiments

September 25, 2025September 25, 2025npj Digital Medicine

The rapid development of AI solutions reveals opportunities to address the underdiagnosis and poor management of chronic conditions in developing settings. Using the method of simulated patients and experimental designs, we evaluate the quality,…

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Multimodal foundation model and benchmark for comprehensive retinal OCT image analysis

Multimodal foundation model and benchmark for comprehensive retinal OCT image analysis

September 25, 2025September 25, 2025npj Digital Medicine

Artificial intelligence (AI) has become a fundamental tool for assisting clinicians in analyzing ophthalmic images, such as optical coherence tomography (OCT). However, developing AI models often requires extensive annotation, and existing models tend to…

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Developing a thyroid cancer differentiation state classification system using deep residual networks and metabolic signature profiling

Developing a thyroid cancer differentiation state classification system using deep residual networks and metabolic signature profiling

September 25, 2025September 25, 2025npj Digital Medicine

We developed a deep residual network (ResNet) framework to classify thyroid cancer differentiation states by integrating multiomic data and interpretability analysis. Our framework incorporated untargeted metabolomic, whole-exome sequencing, and transcriptomic data from 158 thyroid…

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NeoCLIP: a self-supervised foundation model for the interpretation of neonatal radiographs

NeoCLIP: a self-supervised foundation model for the interpretation of neonatal radiographs

September 25, 2025September 25, 2025npj Digital Medicine

Deep learning has proven to be an excellent tool for interpreting medical images in adults and children. However, it is still underdeveloped for neonates. This study developed NeoCLIP, a novel deep contrastive learning model…

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The two areas that are changing… are information technology and medical technology. Those are the things that the world will be very different 20 years from now than it is today.

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