Recent advances in unbiased metagenomic next-generation sequencing (mNGS) enable simultaneous examination of microbial and host genetic material. We developed a multimodal machine learning-based diagnostic approach to differentiate lung cancer and pulmonary infections by analyzing…
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Preoperative differentiation between xanthogranulomatous cholecystitis (XGC) and gallbladder cancer (GBC) remains challenging due to overlapping clinical and imaging features. This multicenter retrospective study developed a machine learning (ML) model, LIDGAX, using preoperative clinical, imaging,…
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Generative artificial intelligence is revolutionizing digital twin development, enabling virtual patient representations that predict health trajectories, with large language models (LLMs) showcasing untapped clinical forecasting potential. We developed the Digital Twin—Generative Pretrained Transformer (DT-GPT),…
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Globally, drug discovery and development programs are complex, multi-decade long and prohibitively expensive. Artificial intelligence (AI) and other digital health technologies have the potential to enhance and accelerate each stage of drug discovery and…
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Hospital readmission is a key quality metric, yet post-discharge interventions often yield variable results. In the first large-scale randomized evaluation of causal machine learning in a health system, we assessed whether a novel model…
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“Using data sets of attacker-generated commands and responses, these models are trained to mimic server behaviors convincingly. Techniques such as supervised fine-tuning, prompt engineering and low-rank adaptations help tailor these models for specific tasks,”…
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What You Should Know:
– A recent data brief from the American Hospital Association (AHA) and the ASTP/ONC examines the trends in predictive AI adoption, evaluation, and governance using data from 2023 and 2024. The…
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A ten-year investment by Concord Technologies in AI is paying off in major enhancements to their platform. In addition to health care data exchange—which supports all types of documents from faxes to, now, secure…
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What You Should Know:
– Cohere Health, a leader in clinical intelligence solutions, has acquired ZignaAI and launched a new Payment Integrity (PI) Suite, which is anchored by Cohere Validate™. Financial details of the acquisition…
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Breast cancer is a leading cause of cancer-related mortality, with tumor heterogeneity and drug resistance posing significant challenges to treatment. We integrated single-cell RNA sequencing, spatial transcriptomics, and bulk RNA-seq deconvolution to analyze BRCA…
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