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Integrative molecular–radiopathomic characterization of AIRE-driven immune subtypes in bladder cancer

Integrative molecular–radiopathomic characterization of AIRE-driven immune subtypes in bladder cancer

December 14, 2025December 14, 2025
Texas AG sues Epic Systems

Texas AG sues Epic Systems

December 13, 2025December 13, 2025
HIMSSCast: Should GPT-5 be HIPAA compliant, FDA regulated?

HIMSSCast: Should GPT-5 be HIPAA compliant, FDA regulated?

December 13, 2025December 13, 2025
HIMSSCast: New book offers first-person look back on challenging early chapter for healthcare AI

HIMSSCast: New book offers first-person look back on challenging early chapter for healthcare AI

December 13, 2025December 13, 2025
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Tag: Large Language Models

Responsible Artificial Intelligence governance in oncology

Responsible Artificial Intelligence governance in oncology

July 5, 2025July 5, 2025npj Digital Medicine

The use of Artificial Intelligence (AI) in healthcare is expanding rapidly, including in oncology. Although generic AI development and implementation frameworks exist in healthcare, no effective governance models have been reported in oncology. Our…

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The Growing Power of AI Agents

The Growing Power of AI Agents

July 2, 2025July 3, 2025Digital Health Frontier

Since ChatGPT was launched in 2022, the entire world has suddenly taken notice of AI’s capabilities. AI agents use such large language models to actively reshape business, finance, and the healthcare ecosystem. Are we…

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Large language model trained on clinical oncology data predicts cancer progression

Large language model trained on clinical oncology data predicts cancer progression

July 2, 2025July 2, 2025npj Digital Medicine

Subspecialty knowledge barriers have limited the adoption of large language models (LLMs) in oncology. We introduce Woollie, an open-source, oncology-specific LLM trained on real-world data from Memorial Sloan Kettering Cancer Center (MSK) across lung,…

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Retrieval-augmented generation elevates local LLM quality in radiology contrast media consultation

Retrieval-augmented generation elevates local LLM quality in radiology contrast media consultation

July 2, 2025July 2, 2025npj Digital Medicine

Large language models (LLMs) demonstrate significant potential in healthcare applications, but clinical deployment is limited by privacy concerns and insufficient medical domain training. This study investigated whether retrieval-augmented generation (RAG) can improve locally deployable…

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An evaluation framework for ambient digital scribing tools in clinical applications

An evaluation framework for ambient digital scribing tools in clinical applications

June 13, 2025June 14, 2025npj Digital Medicine

Ambient digital scribing (ADS) tools alleviate clinician documentation burden, reducing burnout and enhancing efficiency. As AI-driven ADS tools integrate into clinical workflows, robust governance is essential for ethical and secure deployment. This study proposes…

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How generative AI voice agents will transform medicine

How generative AI voice agents will transform medicine

June 12, 2025June 12, 2025npj Digital Medicine

Generative AI voice agents—conversational systems powered by large language models that can understand and produce natural speech in real time—are poised to transform how health systems engage with patients. While technical and implementation challenges…

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Evaluating evidence-based health information from generative AI using a cross-sectional study with laypeople seeking screening information

Evaluating evidence-based health information from generative AI using a cross-sectional study with laypeople seeking screening information

June 9, 2025June 10, 2025npj Digital Medicine

Large language models (LLMs) are used to seek health information. Guidelines for evidence-based health communication require the presentation of the best available evidence to support informed decision-making. We investigate the prompt-dependent guideline compliance of…

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When investigator meets large language models: a qualitative analysis of cancer patient decision-making journeys

When investigator meets large language models: a qualitative analysis of cancer patient decision-making journeys

June 5, 2025June 5, 2025npj Digital Medicine

Large language models (LLMs) are transforming the landscape of healthcare research, yet their role in qualitative analysis remains underexplored. This study compares human-led and LLM-assisted approaches to analyzing cancer patient narratives, using 33 semi-structured…

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AI Medical Diagnosis: Hybrid Approach Superior

AI Medical Diagnosis: Hybrid Approach Superior

June 5, 2025June 5, 2025DistilINFO Hospital IT

Revolutionary Study Compares Traditional vs. Modern AI
Mass General Brigham researchers have discovered that combining traditional diagnostic systems with modern generative AI creates the most effective approach for medical diagnosis. Their groundbreaking study compared established…

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Racial bias in AI-mediated psychiatric diagnosis and treatment: a qualitative comparison of four large language models

Racial bias in AI-mediated psychiatric diagnosis and treatment: a qualitative comparison of four large language models

June 4, 2025June 5, 2025npj Digital Medicine

Artificial intelligence (AI), particularly large language models (LLMs), is increasingly integrated into mental health care. This study examined racial bias in psychiatric diagnosis and treatment across four leading LLMs: Claude, ChatGPT, Gemini, and NewMes-15…

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