Rapid advances in large language models (LLMs) are transforming the role of students and principal investigators (PIs) in biomedical research. This perspective examines how LLMs can reshape the laboratory model as de facto “Co-PIs”…
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Accurate and comprehensive interpretation of pulmonary embolism (PE) from Computed Tomography Pulmonary Angiography (CTPA) scans remains a clinical challenge due to the limited specificity and structure of existing AI tools. We propose an agent-based…
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We introduce a framework to adapt large language models for medicine: (1) Modeling: breaking down medical workflows into manageable steps; (2) Optimization: optimizing model performance via advanced adaptations; and (3) System engineering: developing agent…
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Cognitive bias accounts for a significant portion of preventable errors in healthcare, contributing to significant patient morbidity and mortality each year. As large language models (LLMs) are introduced into healthcare and clinical decision-making, these…
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Rare gynecological tumors (RGTs) present major clinical challenges due to their low incidence and heterogeneity. The lack of clear guidelines leads to suboptimal management and poor prognosis. Molecular tumor boards accelerate access to effective…
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A critical gap in the adoption of large language models for AI-assisted clinical decisions is the lack of a standardized audit framework to evaluate models for accuracy and bias. Our framework introduces a five-step…
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The use of Artificial Intelligence (AI) in healthcare is expanding rapidly, including in oncology. Although generic AI development and implementation frameworks exist in healthcare, no effective governance models have been reported in oncology. Our…
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Since ChatGPT was launched in 2022, the entire world has suddenly taken notice of AI’s capabilities. AI agents use such large language models to actively reshape business, finance, and the healthcare ecosystem. Are we…
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Subspecialty knowledge barriers have limited the adoption of large language models (LLMs) in oncology. We introduce Woollie, an open-source, oncology-specific LLM trained on real-world data from Memorial Sloan Kettering Cancer Center (MSK) across lung,…
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Large language models (LLMs) demonstrate significant potential in healthcare applications, but clinical deployment is limited by privacy concerns and insufficient medical domain training. This study investigated whether retrieval-augmented generation (RAG) can improve locally deployable…
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