Stroke is a leading cause of global morbidity and mortality, disproportionately impacting lower socioeconomic groups. In this study, we evaluated three generative LLMs—GPT, Claude, and Gemini—across four stages of stroke care: prevention, diagnosis, treatment,…
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Digital health technologies hold significant potential for reducing global healthcare disparities. Large language models (LLMs) offer new opportunities to enhance access to culturally specific healthcare, including traditional Chinese medicine (TCM). This study evaluated the…
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Large Language Models (LLMs) are increasingly used to support cancer patients and clinicians in decision-making. This systematic review investigates how LLMs are integrated into oncology and evaluated by researchers. We conducted a comprehensive search…
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Identifying clusters of people with similar patterns of Multiple Long-Term Conditions (MLTC) could help healthcare services to tailor care. In this population-based study, we developed a pipeline incorporating a DeBERTa language model to generate…
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Rapid advances in large language models (LLMs) are transforming the role of students and principal investigators (PIs) in biomedical research. This perspective examines how LLMs can reshape the laboratory model as de facto “Co-PIs”…
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Accurate and comprehensive interpretation of pulmonary embolism (PE) from Computed Tomography Pulmonary Angiography (CTPA) scans remains a clinical challenge due to the limited specificity and structure of existing AI tools. We propose an agent-based…
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We introduce a framework to adapt large language models for medicine: (1) Modeling: breaking down medical workflows into manageable steps; (2) Optimization: optimizing model performance via advanced adaptations; and (3) System engineering: developing agent…
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Cognitive bias accounts for a significant portion of preventable errors in healthcare, contributing to significant patient morbidity and mortality each year. As large language models (LLMs) are introduced into healthcare and clinical decision-making, these…
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Rare gynecological tumors (RGTs) present major clinical challenges due to their low incidence and heterogeneity. The lack of clear guidelines leads to suboptimal management and poor prognosis. Molecular tumor boards accelerate access to effective…
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A critical gap in the adoption of large language models for AI-assisted clinical decisions is the lack of a standardized audit framework to evaluate models for accuracy and bias. Our framework introduces a five-step…
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