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Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

February 1, 2026February 1, 2026
Weekly Roundup – January 31, 2026

Weekly Roundup – January 31, 2026

January 31, 2026February 1, 2026
Embedding clinical intelligence to help close care gaps

Embedding clinical intelligence to help close care gaps

January 31, 2026January 31, 2026
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

January 31, 2026January 31, 2026
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Tag: John Halamka

Demystifying Natural Language Processing

Demystifying Natural Language Processing

May 1, 2025Digital Health Frontier

NLP enables humans and computers to communicate in ways never imagined a few short years ago. The results have practical implications for anyone working in healthcare.

By John Halamka, M.D., M.S., Diercks President, Mayo Clinic…

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Finding the Best AI Algorithms: Is FDA Approval Enough?

Finding the Best AI Algorithms: Is FDA Approval Enough?

April 17, 2025Digital Health Frontier

Guidelines and guardrails for the safe use of AI require more than regulation. The Coalition for Health AI has created a framework to reduce these risks and improve the safety and effectiveness of these…

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Can Large Language Models Function as Scientific Reasoning Engines?

Can Large Language Models Function as Scientific Reasoning Engines?

April 8, 2025Digital Health Frontier

The capabilities of generative AI continue to grow.  Using them wisely will likely improve clinical decision making.

By Paul Cerrato, MA, senior research analyst and communications specialist and John Halamka, M.D., Diercks President, Mayo Clinic…

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Redefining the Nature of Disease

Redefining the Nature of Disease

April 1, 2025Digital Health Frontier

The Oxford Dictionary says disease is a disorder of structure or function, especially one that has a known cause and a distinctive group of symptoms, signs, or anatomical changes. It’s time to rethink that…

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Reexamining the Evidence Behind Evidence-Based Medicine, Part 2

Reexamining the Evidence Behind Evidence-Based Medicine, Part 2

April 1, 2025Digital Health Frontier

In part one, we discussed the shortcomings of evidence-based medicine and the disconnect between RCTs and bedside clinical care. Part 2 explores possible solutions, including machine learning based algorithms. 

By Paul Cerrato, MA, senior research…

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Reexamining the Evidence Behind Evidence-Based Medicine, Part 1

Reexamining the Evidence Behind Evidence-Based Medicine, Part 1

March 25, 2025Digital Health Frontier

Evidence-based medicine has benefited patients in countless ways, but there’s a disconnect between EBM and the clinical care that is typically delivered at the bedside. Pragmatic, real-world trials and AI-based algorithms may help solve…

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Demystifying Artificial Neural Networks

Demystifying Artificial Neural Networks

March 19, 2025Digital Health Frontier

In part 2 of our series on the basics of digital technology, we explore the deep learning tools that can improve medical image analysis and much more.

By John Halamka, M.D., President, Mayo Clinic Platform…

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Demystifying Machine Learning

Demystifying Machine Learning

March 12, 2025Digital Health Frontier

In this new series, we pull back the curtain on the Wizard of Oz to provide plain English explanations about machine learning, artificial neural networks, natural language processing, large language models, and related technology.

By Paul…

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Comparing Large Language Models in Healthcare - Mayo Clinic Platform

Comparing Large Language Models in Healthcare – Mayo Clinic Platform

February 18, 2025February 19, 2025Digital Health Frontier

Given their tendency to invent “facts,” several researchers have begun comparing their strengths and weaknesses.

By John Halamka, M.D., President, Mayo Clinic Platform and Paul Cerrato, MA, senior research analyst and communications specialist, Mayo Clinic…

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Developing the Skills to Write for Publication - Mayo Clinic Platform

Developing the Skills to Write for Publication – Mayo Clinic Platform

January 28, 2025January 29, 2025Digital Health Frontier

A well-reasoned, coherent thesis is not enough to convince editorial gatekeepers to accept your article. Consider these additional suggestions.

By Paul Cerrato, MA, senior research analyst and communications specialist, Mayo Clinic Platform, and John Halamka,…

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