Intensive longitudinal sampling enhances subjective data collection by capturing real-time, dynamic inputs in natural settings, complementing traditional methods. This study evaluates the feasibility of using daily self-reported app data to assess clinical improvement among…
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Traditional disease classification models often disregard the clinical significance of misclassifications and lack interpretability. To overcome these challenges, we propose a hierarchical prototypical decision tree (HPDT) for skin lesion classification. HPDT combines prototypical networks…
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Aging affects the 12-lead electrocardiogram (ECG) and correlates with cardiovascular disease (CVD). AI-ECG models estimate aging effects as a novel biomarker but have only been evaluated on single ECGs—without utilizing longitudinal data. We validated…
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Remote, digital cognitive testing on an individual’s own device provides the opportunity to deploy previously understudied but promising cognitive paradigms in preclinical Alzheimer’s disease (AD). The Boston Remote Assessment for NeuroCognitive Health (BRANCH) captures…
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The 12-lead electrocardiogram (ECG) is inexpensive and widely available. Whether conditions across the human disease landscape can be detected using the ECG is unclear. We developed a deep learning denoising autoencoder and systematically evaluated…
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The current approach to fetal anomaly screening is based on biometric measurements derived from individually selected ultrasound images. In this paper, we introduce a paradigm shift that attains human-level performance in biometric measurement by…
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Cardiac wall motion abnormalities (WMA) are strong predictors of mortality, but current screening methods using Q waves from electrocardiograms (ECGs) have limited accuracy and vary across racial and ethnic groups. This study aimed to…
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This retrospective cohort study evaluates the impact of an AI-supported continuous glucose monitoring (CGM) mobile app (“January V2”) on glycemic control and weight management in 944 users, including healthy individuals and those with prediabetes…
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Using administrative claims and electronic health records for observational studies is common but challenging due to data limitations. Researchers rely on phenotype algorithms, requiring labor-intensive chart reviews for validation. This study investigates whether case…
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Neonatal seizures require urgent treatment, but often go undetected without expert EEG monitoring. We have developed and validated a seizure detection model using retrospective EEG data from 332 neonates. A convolutional neural network was…
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