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Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

February 1, 2026February 1, 2026
Weekly Roundup – January 31, 2026

Weekly Roundup – January 31, 2026

January 31, 2026February 1, 2026
Embedding clinical intelligence to help close care gaps

Embedding clinical intelligence to help close care gaps

January 31, 2026January 31, 2026
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

January 31, 2026January 31, 2026
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Tag: Digital medicine

Preserving information while respecting privacy through an information theoretic framework for synthetic health data generation

Preserving information while respecting privacy through an information theoretic framework for synthetic health data generation

January 23, 2025January 23, 2025npj Digital Medicine

Generating synthetic data from medical records is a complex task intensified by patient privacy concerns. In recent years, multiple approaches have been reported for the generation of synthetic data, however, limited attention was given…

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Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies

Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies

January 22, 2025January 22, 2025npj Digital Medicine

This randomized, controlled trial evaluated the impact of plaque visualization combined with daily tasks on cardiovascular risk profile and included 240 participants with coronary arterial disease. The intervention group received the PreventiPlaque app during…

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Equitable artificial intelligence for glaucoma screening with fair identity normalization

Equitable artificial intelligence for glaucoma screening with fair identity normalization

January 20, 2025January 21, 2025npj Digital Medicine

Glaucoma is the leading cause of irreversible blindness globally. Research indicates a disproportionate impact of glaucoma on racial and ethnic minorities. Existing deep learning models for glaucoma detection might not achieve equitable performance across…

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Computational frameworks transform antagonism to synergy in optimizing combination therapies

Computational frameworks transform antagonism to synergy in optimizing combination therapies

January 19, 2025January 19, 2025npj Digital Medicine

While drug combinations are increasingly important in disease treatment, predicting their therapeutic interactions remains challenging. This review systematically analyzes computational methods for predicting drug combination effects through multi-omics data integration. We comprehensively assess key…

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Clinical entity augmented retrieval for clinical information extraction

Clinical entity augmented retrieval for clinical information extraction

January 19, 2025January 19, 2025npj Digital Medicine

Large language models (LLMs) with retrieval-augmented generation (RAG) have improved information extraction over previous methods, yet their reliance on embeddings often leads to inefficient retrieval. We introduce CLinical Entity Augmented Retrieval (CLEAR), a RAG…

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Advances in the estimation of body fat percentage using an artificial intelligence 2D-photo method

Advances in the estimation of body fat percentage using an artificial intelligence 2D-photo method

January 18, 2025January 19, 2025npj Digital Medicine

There is a growing need to evaluate the agreement between the field methods and integrate artificial intelligence (AI) using two-dimensional (2D) photos for enhanced real-world analysis. This study evaluated the agreement between AI-2D photos…

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A pathway from fragmentation to interoperability through standards-based enterprise architecture to enhance patient safety

A pathway from fragmentation to interoperability through standards-based enterprise architecture to enhance patient safety

January 18, 2025January 18, 2025npj Digital Medicine

Creating an ontology is the essential step in natural language processing (NLP). To improve patient safety in this era of generative AI, it is crucial to develop a standards-driven, ontology-based architecture for patient safety…

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Survey and perspective on verification, validation, and uncertainty quantification of digital twins for precision medicine

Survey and perspective on verification, validation, and uncertainty quantification of digital twins for precision medicine

January 18, 2025January 18, 2025npj Digital Medicine

Digital twins in precision medicine provide tailored health recommendations by simulating patient-specific trajectories and interventions. We examine the critical role of Verification, Validation, and Uncertainty Quantification (VVUQ) for digital twins in ensuring safety and…

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Fusing multispectral information for retinal layer segmentation

Fusing multispectral information for retinal layer segmentation

January 17, 2025January 18, 2025npj Digital Medicine

Extensive research on retinal layer segmentation (RLS) using deep learning (DL) is mostly approaching a performance plateau, primarily due to reliance on structural information alone. To address the present situation, we conduct the first…

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A scoping review of robustness concepts for machine learning in healthcare

A scoping review of robustness concepts for machine learning in healthcare

January 17, 2025January 18, 2025npj Digital Medicine

While machine learning (ML)-based solutions—often referred to as artificial intelligence (AI) solutions—have demonstrated comparable or superior performance to human experts across various healthcare applications, their vulnerability to perturbations and stability to variations due to…

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Developments in medical technology have long been confined to procedural or pharmaceutical advances, while neglecting a most basic and essential component of medicine: patient information management.

John Doolittle

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