Rare diseases (RD) affect 3.5–5.9% of the global population, yet patients often endure a diagnostic odyssey averaging around 5–6 years, navigating multiple specialties and referrals. This study investigates the use of information content (IC)…
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Many workforces are exposed to traumatic events which can precipitate the development of depression, anxiety and posttraumatic stress symptoms. This randomized controlled trial aimed to evaluate if an app-based version of the Skills for…
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Multimodal models have enabled the integration of digital pathology, radiology, clinical information, and omics data to enhance Colorectal cancer (CRC) care. This systematic review critically appraises Multimodal digital pathology techniques applied in CRC, their…
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Clinical decision-making often simplifies continuous risk data into discrete levels using round-number thresholds. These simplifications can distort risk assessments. To systematically uncover these distortions, we develop an interpretable machine learning model that identifies anomalies…
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Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are critical clinical events that necessitate prompt intervention, yet their detection remains challenging in primary care, especially in resource-limited regions where a lack of awareness leads…
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Two recent studies in surgical AI video analysis show divergent outcomes based on user expertise and AI explainability. While both demonstrate improved accuracy with AI-assistance, differences in trust and transparency critically shaped impact. This…
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This study introduces a machine learning framework to predict effective antiviral combinations for influenza A. It identifies Pimodivir with Epinephrine or L-Adrenaline as synergistic agents, confirmed by experiments demonstrating increased binding affinity and viral…
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Careful selection of skin lesions that require expert evaluation is important for early skin cancer detection. Yet challenges include lack of cost-effective asymptomatic screening, geographical inequality in access to specialty dermatology, and long wait…
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Chronic pain (CP) is a debilitating condition that extends beyond persistent pain, influenced by physiological and psychological factors. However, clinical trials often evaluate outcomes solely on self-reported pain amplitude. To address this, we aimed…
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Atrial fibrillation (AF) is the most common arrhythmia worldwide and is associated with significant morbidity and mortality. FibriCheck is a medical analysis platform that uses an end-to-end algorithm to detect AF based on photoplethysmography…
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