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Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

February 1, 2026February 1, 2026
Weekly Roundup – January 31, 2026

Weekly Roundup – January 31, 2026

January 31, 2026February 1, 2026
Embedding clinical intelligence to help close care gaps

Embedding clinical intelligence to help close care gaps

January 31, 2026January 31, 2026
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

January 31, 2026January 31, 2026
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Tag: Digital medicine

Predicting response to neoadjuvant chemotherapy in muscle-invasive bladder cancer via interpretable multimodal deep learning

Predicting response to neoadjuvant chemotherapy in muscle-invasive bladder cancer via interpretable multimodal deep learning

March 22, 2025npj Digital Medicine

Building accurate prediction models and identifying predictive biomarkers for treatment response in Muscle-Invasive Bladder Cancer (MIBC) are essential for improving patient survival but remain challenging due to tumor heterogeneity, despite numerous related studies. To…

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Synthetic bone marrow images augment real samples in developing acute myeloid leukemia microscopy classification models

Synthetic bone marrow images augment real samples in developing acute myeloid leukemia microscopy classification models

March 22, 2025npj Digital Medicine

High-quality image data is essential for training deep learning (DL) classifiers, yet data sharing is often limited by privacy concerns. We hypothesized that generative adversarial networks (GANs) could synthesize bone marrow smear (BMS) images…

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Digital pathways connecting social and biological factors to health outcomes and equity

Digital pathways connecting social and biological factors to health outcomes and equity

March 20, 2025npj Digital Medicine

Digital pathways extend conventional connections between social and biological factors and health outcomes, significantly influencing health equity. Data representation bias and distribution shifts are key mechanisms through which determinants of health impact generalizability of…

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Examining human-AI interaction in real-world healthcare beyond the laboratory

Examining human-AI interaction in real-world healthcare beyond the laboratory

March 19, 2025npj Digital Medicine

Artificial Intelligence (AI) is revolutionizing healthcare, but its true impact depends on seamless human interaction. While most research focuses on technical metrics, we lack frameworks to measure the compatibility or synergy of real-world human-AI…

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Interpretable personalized surgical recommendation with joint consideration of multiple decisional dimensions

Interpretable personalized surgical recommendation with joint consideration of multiple decisional dimensions

March 19, 2025npj Digital Medicine

Surgical planning can be highly complicated and personalized, where a surgeon needs to balance multiple decisional dimensions including surgical effectiveness, risk, cost, and patient’s conditions and preferences. Turning to artificial intelligence is a great…

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Wearable data reveals distinct characteristics of individuals with persistent symptoms after a SARS-CoV-2 infection

Wearable data reveals distinct characteristics of individuals with persistent symptoms after a SARS-CoV-2 infection

March 19, 2025npj Digital Medicine

Understanding the factors associated with persistent symptoms after SARS-CoV-2 infection is critical to improving long-term health outcomes. Using a wearable-derived behavioral and physiological dataset (n = 20,815), we identified individuals characterized by self-reported persistent fatigue and…

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Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy

Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy

March 19, 2025npj Digital Medicine

Demonstrating cardiovascular (CV) benefits with lipid-lowering therapy (LLT) requires long-term randomized clinical trials (RCTs) with thousands of patients. Innovative approaches such as in silico trials applying a disease computational model to virtual patients receiving…

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Cross sectional pilot study on clinical review generation using large language models

Cross sectional pilot study on clinical review generation using large language models

March 19, 2025npj Digital Medicine

As the volume of medical literature accelerates, necessitating efficient tools to synthesize evidence for clinical practice and research, the interest in leveraging large language models (LLMs) for generating clinical reviews has surged. However, there…

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Consternation as Congress proposal for autonomous prescribing AI coincides with the haphazard cuts at the FDA

Consternation as Congress proposal for autonomous prescribing AI coincides with the haphazard cuts at the FDA

March 18, 2025npj Digital Medicine

We live in interesting regulatory times. In January, a bill was introduced to the US Congress proposing that AI “can qualify as a practitioner eligible to prescribe drugs” if overseen by the States and…

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Preliminary analysis of the impact of lab results on large language model generated differential diagnoses

Preliminary analysis of the impact of lab results on large language model generated differential diagnoses

March 18, 2025npj Digital Medicine

Differential diagnosis (DDx) is crucial for medicine as it helps healthcare providers systematically distinguish between conditions that share similar symptoms. This study evaluates the influence of lab test results on DDx accuracy generated by…

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It all comes back to helping patients. That's the reason why we have an innovations office. We have some of the best physicians, scientists and engineers in the world right here in Cleveland who come up with brilliant ideas every day. And we need a way of bringing these to the market to help patients today and in the future. We want to reduce healthcare costs if we can come up with a less expensive way of doing something. We need to innovate around what we traditionally do but then also look at new avenues that we can explore to impact patient care.

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