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Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

February 1, 2026February 1, 2026
Weekly Roundup – January 31, 2026

Weekly Roundup – January 31, 2026

January 31, 2026February 1, 2026
Embedding clinical intelligence to help close care gaps

Embedding clinical intelligence to help close care gaps

January 31, 2026January 31, 2026
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

January 31, 2026January 31, 2026
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Tag: Digital medicine

Development and validation of an interpretable risk prediction model for the early classification of thalassemia

Development and validation of an interpretable risk prediction model for the early classification of thalassemia

June 10, 2025June 10, 2025npj Digital Medicine

Thalassemia is an inherited blood disorder. Current diagnostic methods mainly rely on sophisticated equipment and specifically trained technicians. This study aims to identify and genotype thalassemia by applying machine learning (ML) algorithms to routine…

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A cross population study of retinal aging biomarkers with longitudinal pre-training and label distribution learning

A cross population study of retinal aging biomarkers with longitudinal pre-training and label distribution learning

June 10, 2025June 10, 2025npj Digital Medicine

Retinal age has emerged as a promising biomarker of aging, offering a non-invasive and accessible assessment tool. We developed a deep learning model to estimate retinal age with enhanced accuracy, leveraging retinal images from…

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Empirical evaluation of artificial intelligence distillation techniques for ascertaining cancer outcomes from electronic health records

Empirical evaluation of artificial intelligence distillation techniques for ascertaining cancer outcomes from electronic health records

June 10, 2025June 11, 2025npj Digital Medicine

Phenotypic information for cancer research is embedded in unstructured electronic health records (EHR), requiring effort to extract. Deep learning models can automate this but face scalability issues due to privacy concerns. We evaluated techniques…

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Evaluating evidence-based health information from generative AI using a cross-sectional study with laypeople seeking screening information

Evaluating evidence-based health information from generative AI using a cross-sectional study with laypeople seeking screening information

June 9, 2025June 10, 2025npj Digital Medicine

Large language models (LLMs) are used to seek health information. Guidelines for evidence-based health communication require the presentation of the best available evidence to support informed decision-making. We investigate the prompt-dependent guideline compliance of…

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SQL on FHIR - Tabular views of FHIR data using FHIRPath

SQL on FHIR – Tabular views of FHIR data using FHIRPath

June 9, 2025June 9, 2025npj Digital Medicine

Challenges exist with the adoption of Fast Healthcare Interoperability Resources (FHIR) within analytics, including the difficulty in transforming complex data structures, and performance issues when querying large datasets in their native JSON or XML…

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Foundation versus domain-specific models for left ventricular segmentation on cardiac ultrasound

Foundation versus domain-specific models for left ventricular segmentation on cardiac ultrasound

June 6, 2025June 6, 2025npj Digital Medicine

The Segment Anything Model (SAM) was fine-tuned on the EchoNet-Dynamic dataset and evaluated on external transthoracic echocardiography (TTE) and Point-of-Care Ultrasound (POCUS) datasets from CAMUS (University Hospital of St Etienne) and Mayo Clinic (99…

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Machine learning to predict penumbra core mismatch in acute ischemic stroke using clinical note data

Machine learning to predict penumbra core mismatch in acute ischemic stroke using clinical note data

June 6, 2025June 6, 2025npj Digital Medicine

In acute ischemic stroke due to large-vessel occlusion (AIS-LVO), late-window endovascular thrombectomy (EVT) decisions depend on penumbra-to-core (P:C) mismatch from computed tomographic perfusion (CTP). We developed multiple machine learning (ML) models to predict P:C…

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A “True Lifecycle Approach” towards governing healthcare AI with the GCC as a global governance model

A “True Lifecycle Approach” towards governing healthcare AI with the GCC as a global governance model

June 6, 2025June 6, 2025npj Digital Medicine

This paper proposes a “True Lifecycle Approach” (TLA) towards governing healthcare AI. The TLA governance model embeds core healthcare law principles—like informed consent, liability, and patient rights—throughout AI’s development, deployment, and use. Unlike narrow…

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When investigator meets large language models: a qualitative analysis of cancer patient decision-making journeys

When investigator meets large language models: a qualitative analysis of cancer patient decision-making journeys

June 5, 2025June 5, 2025npj Digital Medicine

Large language models (LLMs) are transforming the landscape of healthcare research, yet their role in qualitative analysis remains underexplored. This study compares human-led and LLM-assisted approaches to analyzing cancer patient narratives, using 33 semi-structured…

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Identifying and mitigating algorithmic bias in the safety net

Identifying and mitigating algorithmic bias in the safety net

June 5, 2025June 5, 2025npj Digital Medicine

Algorithmic bias occurs when predictive model performance varies meaningfully across sociodemographic classes, exacerbating systemic healthcare disparities. NYC Health + Hospitals, an urban safety net system, assessed bias in two binary classification models in our…

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The physical space of the hospital will be gradually digitized until virtually every object and sensor becomes part of the so-called 'Internet of Things.' These innovations can broadly be categorized as either clinical or experiential, though some will be both. Clinical innovations will involve gathering ever more "signals" from the patient (infrared, sound, electrophysiology, pulse-oximeter, facial expression, etc.) to be sifted in real time through machine-learning algorithms that will help physicians refine their understanding of diagnosis and prognosis in ways we can only imagine today. Experiential innovations will allow health systems and their partners to take a page from Netflix, using the engagement opportunity of the acute care episode to stream digital content to patients and families through TVs, tablets and their own devices from home.

Daniel Durand

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