Infantile epileptic spasm syndrome (IESS) is a severe neurological disorder characterized by epileptic spasms (ES). Timely diagnosis is crucial, but it is often delayed due to symptom misidentification. Smartphone videos can aid in diagnosis,…
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Stroke remains a leading global cause of mortality, with ischemic stroke as the most common subtype. Atrial fibrillation (AF) increases ischemic stroke risk due to thrombus formation in the left atrium (LA), particularly in…
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The success of AI solutions in health systems depends on governance from use case inception through deployment and auditing. This proposed early pipeline governance framework for vendor AI solutions highlights a four-pronged approach: strategic…
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Reproductive aging impacts women’s health through fertility decline, disease susceptibility, and systemic aging. This study explores the retinal age gap—the difference between predicted retinal age and chronological age—as a novel biomarker for reproductive aging….
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As digital biomarkers gain traction in Alzheimer’s disease (AD) diagnosis, understanding recent advancements is crucial. This review conducts a bibliometric analysis of 431 studies from five online databases: Web of Science, PubMed, Embase, IEEE…
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Digital health technology (DHT) tools for Parkinson’s disease (PD) e.g., smartphones and wearables were used for remote and frequent measurement of motor signs in the phase 2 PASADENA study of the anti-alpha-synuclein monoclonal antibody…
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Combined immunodeficiencies (CID) and common variable immunodeficiencies (CVID), prevalent yet substantially underdiagnosed primary immunodeficiencies, necessitate improved early detection. Leveraging large-scale electronic health records (EHR) from four nationwide US cohorts, we developed a novel causal…
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The ethical integration of artificial intelligence (AI) in healthcare necessitates addressing fairness. AI fairness involves mitigating biases in AI and leveraging AI to promote equity. Despite advancements, significant disconnects persist between technical solutions and…
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The widespread adoption of Electronic Health Records (EHRs) and deep learning, particularly through Self-Supervised Representation Learning (SSRL) for categorical data, has transformed clinical decision-making. This scoping review, following PRISMA-ScR guidelines, examines 46 studies published…
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Subjective cognitive decline (SCD) is a potential early marker of neurodegeneration, with negative affective states such as depression and anxiety significantly contributing to cognitive impairment. Digital treatments show promise, yet evidence of their use…
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