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Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

February 1, 2026February 1, 2026
Weekly Roundup – January 31, 2026

Weekly Roundup – January 31, 2026

January 31, 2026February 1, 2026
Embedding clinical intelligence to help close care gaps

Embedding clinical intelligence to help close care gaps

January 31, 2026January 31, 2026
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

January 31, 2026January 31, 2026
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Tag: Digital medicine

An end-to-end multifunctional AI platform for intraoperative diagnosis

An end-to-end multifunctional AI platform for intraoperative diagnosis

July 20, 2025July 20, 2025npj Digital Medicine

Intraoperative frozen section diagnosis provides essential, real-time histological insights to guide surgical decisions. However, the quality of these time-sensitive sections is often suboptimal, posing significant diagnostic challenges for pathologists. To address these limitations, we…

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Demographic inaccuracies and biases in the depiction of patients by artificial intelligence text-to-image generators

Demographic inaccuracies and biases in the depiction of patients by artificial intelligence text-to-image generators

July 19, 2025July 19, 2025npj Digital Medicine

The wide usage of artificial intelligence (AI) text-to-image generators raises concerns about the role of AI in amplifying misconceptions in healthcare. This study therefore evaluated the demographic accuracy and potential biases in the depiction…

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A randomized controlled trial of a digital cognitive behavioral therapy for insomnia for older adults

A randomized controlled trial of a digital cognitive behavioral therapy for insomnia for older adults

July 19, 2025July 19, 2025npj Digital Medicine

Older adults with insomnia face considerable challenges accessing treatment given limited availability to first-line therapy (Cognitive-Behavioral Therapy for Insomnia, CBT-I). This study evaluated the efficacy of Sleep Healthy Using the Internet for Older Adults…

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Unlocking efficiency in real-world collaborative studies: a multi-site international study with one-shot lossless GLMM algorithm

Unlocking efficiency in real-world collaborative studies: a multi-site international study with one-shot lossless GLMM algorithm

July 19, 2025July 19, 2025npj Digital Medicine

The widespread adoption of real-world data has given rise to numerous healthcare-distributed research networks, but multi-site analyses still face administrative burdens and data privacy challenges. In response, we developed a Collaborative One-shot Lossless Algorithm…

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Systematic review and meta-analysis of deep learning for MSI-H in colorectal cancer whole slide images

Systematic review and meta-analysis of deep learning for MSI-H in colorectal cancer whole slide images

July 19, 2025July 19, 2025npj Digital Medicine

This meta-analysis evaluated diagnostic performance of deep learning (DL) algorithms using whole slide images (WSIs) for detecting microsatellite instability-high (MSI-H) in colorectal cancer (CRC). PubMed, Embase, and Web of Science were searched until January…

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Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model

Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model

July 19, 2025July 19, 2025npj Digital Medicine

Artificial intelligence applications in liver pathology remain limited, with existing tools either narrowly focused or lacking external validation. This study introduces HOTSPoT, an open-source, validated transformer-based model for automated segmentation of portal tracts in…

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Commercialization of medical artificial intelligence technologies: challenges and opportunities

Commercialization of medical artificial intelligence technologies: challenges and opportunities

July 18, 2025July 18, 2025npj Digital Medicine

Artificial intelligence (AI) is already having a significant impact on healthcare. For example, AI-guided imaging can improve the diagnosis/treatment of vascular diseases, which affect over 200 million people globally. Recently, Chiu and colleagues (2024)…

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Evaluation of an integrated digital and mobile intervention to improve outcomes for patients with moderate to severe COPD

Evaluation of an integrated digital and mobile intervention to improve outcomes for patients with moderate to severe COPD

July 18, 2025July 18, 2025npj Digital Medicine

Chronic obstructive pulmonary disease (COPD) leads to high rates of emergency department (ED) visits and hospitalizations. This study evaluated a community-based digital health intervention’s association with acute care utilization among patients with moderate to…

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Large language model integrations in cancer decision-making: a systematic review and meta-analysis

Large language model integrations in cancer decision-making: a systematic review and meta-analysis

July 18, 2025July 18, 2025npj Digital Medicine

Large Language Models (LLMs) are increasingly used to support cancer patients and clinicians in decision-making. This systematic review investigates how LLMs are integrated into oncology and evaluated by researchers. We conducted a comprehensive search…

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Negative control-calibrated difference-in-difference analyses: addressing unmeasured confounding in RWD with application to racial/ethnic differences

Negative control-calibrated difference-in-difference analyses: addressing unmeasured confounding in RWD with application to racial/ethnic differences

July 18, 2025July 18, 2025npj Digital Medicine

Real-world data (RWD) from electronic health records and digital health databases present unique opportunities to study causal effects in healthcare. While Difference-in-Differences (DiD) analysis is widely used for such analyses, it can be biased…

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The physical space of the hospital will be gradually digitized until virtually every object and sensor becomes part of the so-called 'Internet of Things.' These innovations can broadly be categorized as either clinical or experiential, though some will be both. Clinical innovations will involve gathering ever more "signals" from the patient (infrared, sound, electrophysiology, pulse-oximeter, facial expression, etc.) to be sifted in real time through machine-learning algorithms that will help physicians refine their understanding of diagnosis and prognosis in ways we can only imagine today. Experiential innovations will allow health systems and their partners to take a page from Netflix, using the engagement opportunity of the acute care episode to stream digital content to patients and families through TVs, tablets and their own devices from home.

Daniel Durand

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