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Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

Diverging trajectories of trust in healthcare and on-line information seeking: what’s next with LLMs

February 1, 2026February 1, 2026
Weekly Roundup – January 31, 2026

Weekly Roundup – January 31, 2026

January 31, 2026February 1, 2026
Embedding clinical intelligence to help close care gaps

Embedding clinical intelligence to help close care gaps

January 31, 2026January 31, 2026
Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

Impact of Mobilization Facilitated by Wearable Device Enhanced Patient Monitoring/Electrophysiology Pod–Based Feedback on Postoperative Complications Following Colorectal Cancer Surgery: Randomized Controlled Trial

January 31, 2026January 31, 2026
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Category: npj Digital Medicine

A strategy for cost-effective large language model use at health system-scale

A strategy for cost-effective large language model use at health system-scale

November 18, 2024November 18, 2024npj Digital Medicine

Large language models (LLMs) can optimize clinical workflows; however, the economic and computational challenges of their utilization at the health system scale are underexplored. We evaluated how concatenating queries with multiple clinical notes and…

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Simulating A/B testing versus SMART designs for LLM-driven patient engagement to close preventive care gaps

Simulating A/B testing versus SMART designs for LLM-driven patient engagement to close preventive care gaps

November 18, 2024November 18, 2024npj Digital Medicine

Population health initiatives often rely on cold outreach to close gaps in preventive care, such as overdue screenings or immunizations. Tailoring messages to diverse patient populations remains challenging, as traditional A/B testing requires large…

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Cost-effectiveness analysis of mHealth applications for depression in Germany using a Markov cohort simulation

Cost-effectiveness analysis of mHealth applications for depression in Germany using a Markov cohort simulation

November 17, 2024November 17, 2024npj Digital Medicine

Regulated mobile health applications are called digital health applications (“DiGA”) in Germany. To qualify for reimbursement by statutory health insurance companies, DiGA have to prove positive care effects in scientific studies. Since the empirical…

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Multisource representation learning for pediatric knowledge extraction from electronic health records

Multisource representation learning for pediatric knowledge extraction from electronic health records

November 13, 2024November 13, 2024npj Digital Medicine

Electronic Health Record (EHR) systems are particularly valuable in pediatrics due to high barriers in clinical studies, but pediatric EHR data often suffer from low content density. Existing EHR code embeddings tailored for the…

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The effects of a digital health intervention on patient activation in chronic kidney disease

The effects of a digital health intervention on patient activation in chronic kidney disease

November 12, 2024November 12, 2024npj Digital Medicine

My Kidneys & Me (MK&M), a digital health intervention delivering specialist health and lifestyle education for people with CKD, was developed and its effects tested (SMILE-K trial, ISRCTN18314195, 18/12/2020). 420 adult patients with CKD…

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Simulated misuse of large language models and clinical credit systems

Simulated misuse of large language models and clinical credit systems

November 11, 2024November 11, 2024npj Digital Medicine

In the future, large language models (LLMs) may enhance the delivery of healthcare, but there are risks of misuse. These methods may be trained to allocate resources via unjust criteria involving multimodal data -…

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Accuracy and efficiency of drilling trajectories with augmented reality versus conventional navigation randomized crossover trial

Accuracy and efficiency of drilling trajectories with augmented reality versus conventional navigation randomized crossover trial

November 10, 2024November 10, 2024npj Digital Medicine

Conventional navigation systems (CNS) in surgery require strong spatial cognitive abilities and hand-eye coordination. Augmented Reality Navigation Systems (ARNS) provide 3D guidance and may overcome these challenges, but their accuracy and efficiency compared to…

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Post-marketing surveillance of anticancer drugs using natural language processing of electronic medical records

Post-marketing surveillance of anticancer drugs using natural language processing of electronic medical records

November 10, 2024November 10, 2024npj Digital Medicine

This study demonstrates that adverse events (AEs) extracted using natural language processing (NLP) from clinical texts reflect the known frequencies of AEs associated with anticancer drugs. Using data from 44,502 cancer patients at a…

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Artificial intelligence assisted operative anatomy recognition in endoscopic pituitary surgery

Artificial intelligence assisted operative anatomy recognition in endoscopic pituitary surgery

November 9, 2024November 9, 2024npj Digital Medicine

Pituitary tumours are surrounded by critical neurovascular structures and identification of these intra-operatively can be challenging. We have previously developed an AI model capable of sellar anatomy segmentation. This study aims to apply this…

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Ehealth interactive intervention in promoting safer sex among men who have sex with men

Ehealth interactive intervention in promoting safer sex among men who have sex with men

November 9, 2024November 9, 2024npj Digital Medicine

Men who have sex with men (MSM) who use dating applications (apps) have higher rates of engaging in condomless anal sex than those who do not. Therefore, we conducted a two-arm randomized controlled trial…

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The most evolutionary change coming to hospital rooms of the future is that they will be in your own home. For certain acute conditions, the hospital room will come to you. You will be able to convalesce in the comfort of your own home by using portable technology and next-generation healthcare equipment. This will allow for high quality care to be rendered in a person's home by medical professionals both onsite and virtually.

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