Evaluating the Clinical Effectiveness and Patient Experience of a Large Language Model–Based Digital Tool for Home-Based Blood Pressure Management: Mixed Methods Study

Evaluating the Clinical Effectiveness and Patient Experience of a Large Language Model–Based Digital Tool for Home-Based Blood Pressure Management: Mixed Methods Study

Background: Hypertension, one of the most common cardiovascular conditions worldwide, necessitates comprehensive management due to its association with multiple health risks. Effective control often involves lifestyle changes and continuous monitoring, yet many individuals struggle…

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Within- and Between-Individual Compliance in Mobile Health: Joint Modeling Approach to Nonrandom Missingness in an Intensive Longitudinal Observational Study

Within- and Between-Individual Compliance in Mobile Health: Joint Modeling Approach to Nonrandom Missingness in an Intensive Longitudinal Observational Study

Background: Missing data are inevitable in mobile health (mHealth) and ubiquitous health (uHealth) research and are often driven by distinct within- and between-person factors that influence compliance. Understanding these distinct mechanisms underlying nonresponse can…

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Temporal Trajectories in Sleep, Temperature Trends, Cardiorespiratory, and Activity Metrics Measured via Oura Ring During Pregnancy: Large-Scale Observational Analysis

Temporal Trajectories in Sleep, Temperature Trends, Cardiorespiratory, and Activity Metrics Measured via Oura Ring During Pregnancy: Large-Scale Observational Analysis

Background: Pregnancy and childbirth involve significant health challenges, including preventable maternal deaths, severe complications, and disparities tied to social determinants, emphasizing the need for improved maternal care. Pregnancy could benefit from a more comprehensive,…

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A Culturally and Linguistically Tailored Intervention to Improve Diabetes-Related Outcomes in Chinese Americans With Type 2 Diabetes: Pilot Randomized Controlled Trial

A Culturally and Linguistically Tailored Intervention to Improve Diabetes-Related Outcomes in Chinese Americans With Type 2 Diabetes: Pilot Randomized Controlled Trial

Background: Chinese Americans with type 2 diabetes (T2D) face many linguistic, cultural, and social determinants of health–related barriers to accessing evidence-based diabetes interventions. Our team developed the culturally and linguistically tailored Chinese American Research…

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Hybrid Health IT and Telehealth–Delivered Behavioral Weight Loss Services for Primary Care Patients With Cardiovascular Risk Factors: Intervention Component Design and Pragmatic Randomized Feasibility Trial

Hybrid Health IT and Telehealth–Delivered Behavioral Weight Loss Services for Primary Care Patients With Cardiovascular Risk Factors: Intervention Component Design and Pragmatic Randomized Feasibility Trial

Background: Intensive lifestyle interventions (ILI) improve weight loss and cardiovascular risk factors, but health systems face challenges implementing them. Objective: We engaged stakeholders to cocreate and evaluate feasibility of primary care implementation strategies and…

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Bidirectional Associations Between Physical Activity, Sedentary Behavior, and Daily Symptoms in Patients With Chronic Obstructive Pulmonary Disease: Longitudinal Observational Study

Bidirectional Associations Between Physical Activity, Sedentary Behavior, and Daily Symptoms in Patients With Chronic Obstructive Pulmonary Disease: Longitudinal Observational Study

Background: Questionnaire-based symptom assessment may introduce recall bias and lacks bidirectional exploration. This is particularly relevant given the unclear direction of the associations between physical activity (PA), sedentary time (ST) and symptoms in patients…

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