DoseCalc® OnLine DataBase of Oncology Regimens and calculation software contains many common combination treatment regimens for solid tumors and adult leukemias and is designed to serve as a concise database reference for use by oncology healthcare professionals. DoseCalc OnLine is intended as a general reference only to supplement the existing knowledge of healthcare professionals. While the DoseCalc OnLine provides resources for quick access to referenced protocols, it should be recognized that many combination cancer regimens have variations.
DoseCalc OnLine does NOT provide criteria for selection of regimens or for assessment of the appropriateness of a regimen for a specific patient. DoseCalc ® OnLine does NOT include information on potential side effects of specific regimens. In short, the DoseCalc OnLine is a limited database of information and a dosage calculator, and is NOT a substitute for the sound clinical judgement of the knowledgable health professional.
Health professionals using these regimens should consult complete prescribing information before using any drug included in a regimen. It should be noted that not all drugs and dosages listed in the regimens are necessarily approved by the Food and Drug Administration (FDA) for use in treating the specific cancer.
Each listed regimen follows the following format:
- Type of cancer
- Protocol Acronym (eg: PAC)
- Listing of drugs in the regimen
- Abbreviations of drugs in regimen
- Dosage schedule for each drug, usually expressed in units of per meter squared of patient body area (eg: mg/m2)
- mg = milligram
- kg = kilogram
- g = gram
- mL = mililiter
- MU = megaunits
- Route of administration for each drug, expressed as:
- IV = IV infusion
- IVB = IV bolus
- CIV = Continous IV infusion
- IM = Intramuscular
- IT = Intrathecal
- PO = Oral
- SC = Subcutaneous
- IV (time) = IV infusion over specific time period
- Dosing time, expressed as:
- H = hour
- D = day
- wk = week
- /1hr = over one hour
- x4 = for four times
- q6h = every 6 hours
- qd = every day
- In reading days, a dash (-) means 'to'.
- eg: D1-4 is read 'day 1 to 4'
- In reading days, a comma (,) means 'and'
- eg: D1,5,12 is read 'days 1,5, and 12'
- Cycles:
- Number and timing or recommended repetitions of therapy are usually expressed as number of days (eg: q28 days)
- Reference:
- Citation for the protocol in abbreviated format
For more information visit http://www.meds.com/DChome.html
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