Neuropsychiatric disorders have complex causes and exhibit considerable individual variability as they develop over time. This suggests the need for a shift from a focus on observable clinical symptoms to a personalized trajectory monitoring…
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Over 25 million U.S. patients with a non-English language preference face unsafe care because discharge instructions and other materials are rarely translated in time. Advances in translation assisted by large language models can close…
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Healthcare communication faces unprecedented challenges as the healthcare workforce is increasingly faced with increased administrative burdens and reduced time with patients. Conversational agents powered by generative AI may offer a potential solution by collecting…
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Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…
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Electronic health records (EHRs) contain rich longitudinal information for clinical decision-making, yet LLMs struggle to reason across patient timelines. We introduce TIMER (Temporal Instruction Modeling and Evaluation for Longitudinal Clinical Records), a method to…
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Clinical decision-making substantially impacts patients’ lives and their quality of life. However, the black-box nature of AI-powered clinical decision support systems (CDSSs) complicates the interpretation of how decisions are derived. Explainable AI (XAI) improves…
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Globally, drug discovery and development programs are complex, multi-decade long and prohibitively expensive. Artificial intelligence (AI) and other digital health technologies have the potential to enhance and accelerate each stage of drug discovery and…
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The neonatal period is critical and stressful, particularly in low-resource settings where existing monitoring methods for newborns are sporadic and labor-intensive. There is a pressing need for an affordable, user-friendly device that offers continuous…
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The rapid development of AI solutions reveals opportunities to address the underdiagnosis and poor management of chronic conditions in developing settings. Using the method of simulated patients and experimental designs, we evaluate the quality,…
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Artificial intelligence (AI) has become a fundamental tool for assisting clinicians in analyzing ophthalmic images, such as optical coherence tomography (OCT). However, developing AI models often requires extensive annotation, and existing models tend to…
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