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A framework for considering the use of generative AI for health

A framework for considering the use of generative AI for health

May 21, 2025May 21, 2025
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Author: npj Digital Medicine

A framework for considering the use of generative AI for health

A framework for considering the use of generative AI for health

May 21, 2025May 21, 2025npj Digital Medicine

This perspective provides a critical framework for evaluating the use of Generative AI (GenAI) in healthcare, informed by two roundtable events and a series of semi-structured expert interviews. By outlining key principles and risks—including…

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A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer

A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer

May 20, 2025May 20, 2025npj Digital Medicine

Few studies have investigated quality of life (QoL) improvements in patients with colorectal cancer or the benefits of digital healthcare interventions. This randomized controlled trial assessed the impact of mobile applications on postoperative QoL…

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A multivariate model incorporating subharmonic measurements for evaluating vocal roughness

A multivariate model incorporating subharmonic measurements for evaluating vocal roughness

May 20, 2025May 20, 2025npj Digital Medicine

The assessment of voice quality plays a critical role in the clinical evaluation of hoarseness. However, no study has established a highly accurate method for the auditory–perceptual judgment of vocal roughness, which is one…

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Deep Gaussian process with uncertainty estimation for microsatellite instability and immunotherapy response prediction from histology

Deep Gaussian process with uncertainty estimation for microsatellite instability and immunotherapy response prediction from histology

May 19, 2025May 19, 2025npj Digital Medicine

Determining tumor microsatellite status has significant clinical value because tumors that are microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) respond well to immune checkpoint inhibitors (ICIs) and oftentimes not to chemotherapeutics. We propose…

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Engaging an advisory board in discussions about the ethical relevance of algorithmic bias and fairness

Engaging an advisory board in discussions about the ethical relevance of algorithmic bias and fairness

May 18, 2025May 19, 2025npj Digital Medicine

We are an interdisciplinary team of researchers that are working to advance algorithmic fairness in the research of opioid use disorders. We discuss challenges that our research team faced when engaging with our Advisory…

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Fair ultrasound diagnosis via adversarial protected attribute aware perturbations on latent embeddings

Fair ultrasound diagnosis via adversarial protected attribute aware perturbations on latent embeddings

May 17, 2025May 17, 2025npj Digital Medicine

Deep learning techniques have significantly enhanced the convenience and precision of ultrasound image diagnosis, particularly in the crucial step of lesion segmentation. However, recent studies reveal that both train-from-scratch models and pre-trained models often…

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Development and prospective implementation of a large language model based system for early sepsis prediction

Development and prospective implementation of a large language model based system for early sepsis prediction

May 17, 2025May 17, 2025npj Digital Medicine

Sepsis is a dysregulated host response to infection with high mortality and morbidity. Early detection and intervention have been shown to improve patient outcomes, but existing computational models relying on structured electronic health record…

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Social determinants of health extraction from clinical notes across institutions using large language models

Social determinants of health extraction from clinical notes across institutions using large language models

May 17, 2025May 17, 2025npj Digital Medicine

Detailed social determinants of health (SDoH) is often buried within clinical text in EHRs. Most current NLP efforts for SDoH have limitations, investigating limited factors, deriving data from a single institution, using specific patient…

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FedWeight: mitigating covariate shift of federated learning on electronic health records data through patients re-weighting

FedWeight: mitigating covariate shift of federated learning on electronic health records data through patients re-weighting

May 17, 2025May 17, 2025npj Digital Medicine

Federated learning (FL) enables collaborative analysis of decentralized medical data while preserving patient privacy. However, the covariate shift from demographic and clinical differences can reduce model generalizability. We propose FedWeight, a novel FL framework…

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Hybrid machine learning for real-time prediction of edema trajectory in large middle cerebral artery stroke

Hybrid machine learning for real-time prediction of edema trajectory in large middle cerebral artery stroke

May 17, 2025May 17, 2025npj Digital Medicine

In treating malignant cerebral edema after a large middle cerebral artery stroke, clinicians need quantitative tools for real-time risk assessment. Existing predictive models typically estimate risk at one, early time point, failing to account…

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The most evolutionary change coming to hospital rooms of the future is that they will be in your own home. For certain acute conditions, the hospital room will come to you. You will be able to convalesce in the comfort of your own home by using portable technology and next-generation healthcare equipment. This will allow for high quality care to be rendered in a person's home by medical professionals both onsite and virtually.

Nick Patel

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